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Results for ATP2B3


Expand for information on ATP2B3

ATP2B3

Description
ATPase plasma membrane Ca2+ transporting 3
Aliases
CFAP39, CLA2, OPCA, PMCA3, PMCA3a, SCAX1

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Tumour suppressor
  • Damaged in 102/7921 TCGA samples
  • Damaged in 23/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • 3 duplicates (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 71 protein(s)
  • Part of zero complexes

miRNA Interactions

  • Interacts with 14 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1114 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials