Home Query results

Results for EPHA3


Expand for information on EPHA3

EPHA3

Description
EPH receptor A3
Aliases
EK4, ETK, ETK1, HEK, HEK4, TYRO4

Gene Identifiers

Entrez ID
Ensembl Gene ID

mRNA Identifiers

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Cancer gene
  • Damaged in 196/7921 TCGA samples
  • Damaged in 49/1291 cell lines

Evolutionary Conservation

  • Last Universal Common Ancestor

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 41 protein(s)
  • Part of at least one complex

miRNA Interactions

  • No miRNA interactions

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1122 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials