Home Query results

Results for GPC3


Expand for information on GPC3

GPC3

Description
glypican 3
Aliases
DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1

Gene Identifiers

Entrez ID
Ensembl Gene ID

Protein Architecture

Disease Mapping

COSMIC
OMIM
Pubmed

Druggability

Driver Information

  • Cancer gene
  • Damaged in 581/7921 TCGA samples
  • Damaged in 5/1291 cell lines

Evolutionary Conservation

  • Metazoans

Gene Duplication

  • No duplicate (60% coverage)

Gene Expression in Tissues

Gene Expression in Cell Lines

Protein Expression in Tissues

Protein Interactions

  • Interacts with 68 protein(s)
  • Part of at least one complex

miRNA Interactions

  • Interacts with 3 miRNAs

Germline Variation vs. Expected

  • Fewer loss of function mutations
  • Fewer damaging SNVs/indels
  • Fewer structural variants

Gene Essentiality

  • Not essential in 1052 cell lines

Gene Function

Drug Target/Biomarker

  • Targeted by 0 drugs
  • Response/resistance in 0 cell lines
  • Response/resistance in 0 trials